A. Molecules of life (A,G)
1. Properties of water
2. Aqueous solutions
a. Solute concentration
b. Acids, bases, pH
3. Carbon & molecular diversity
a. Versatility of carbon in molecular architecture
b. Isomers
c. Functional groups
d. Chemical elements of life
B. Structure and organization of the cell (B,G)
1. Microscopy
2. Prokaryotic and eukaryotic cells
3. Importance of compartmental organization
a. Ribosomes
b. Endomembrane system
i. nucleus
ii. Endoplasmic reticulum
iii. Golgi
iv. Lysosomes
v. Vacuoles
vi. Plasma membrane
vii. Peroxisomes
c. Peroxisomes
d. Mitochondria
e. Chloroplasts
f. Cytoskeleton
4. Structure and organization of biological membranes
a. Models of membrane structure
b. Trafficking of small molecules
c. Selective permeability
d. Diffusion and passive transport
e. Osmosis
f. Facilitated diffusion
g. Active transport
h.
Exocytosis & endocytosis, trafficking of
large
molecules
C. Introduction to metabolism (A, B, C, G)
1. Energy
a. Forms of energy
b. Thermodynamics
2. Enzymes
a. Biological catalysts
b. Enzyme specificity
c. Feedback inhibition
3. Cellular energy & work
4. Cellular respiration
a. Redox
b. Anaerobic respiration, substrate level phosphorylation
c. Aerobic respiration, oxidative phophorylation
d. Photosynthesis, photophosphorylation
D. Genetics and molecular biology (D, E, G)
1. Mitosis
2. Meiosis
3. Mendilian genetics
4. DNA, replication
5. RNA, transcription
6. Protein, translation
7. Microbial models: the genetics of viruses and bacteria
a. Gene regulation prokaryotes
b. DNA technology
i. Cloning
ii. RFLP
iii. Current biotechnology topics
8. Gene structure and regulation in eukaryotes
a. Chromatin and DNA packing
b. Control of gene expression
c. Molecular biology of cancer
9. Genetic regulation of development
a. Differential gene expression
b. Drosophila as a model of genetic control of development
E. Anatomy and physiology of higher vertebrates (A-G)
1. Digestion
2. Circulation and gas exchange
3. Immune system
a. Non-specific response
b. Specific response
c. AIDS
d. Allergy
4. Homeostasis
5. Endocrine system
6. Reproduction
a. Asexual reproduction
b. Sexual reproduction
c. Human reproduction and sexually transmitted diseases
7. Nervous system
a. Neurons, membrane potentials, and synapses
b. Signal integration
8. Sensory and motor mechanisms
a. Sensory receptors
b. Muscles and glands